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Jitendran Muthuswamy

jit@asu.edu

Assoc Professor
Sch Biological & Hlth Sys Engr
Faculty
Mail Code: 9709

ISTB1 181A (Map)
(480)965-1599

Bio

Associate Professor
Harrington Department of Bioengineering
Ira A. Fulton School of Engineering

Muthuswamy's research interests are in the areas of Microelectromechanical systems (MEMS) for Neural communication, and plasticity in the central nervous system. The Engineering and Neuroscience research efforts in his lab are primarily directed towards understanding and treating brain dysfunction. However, our understanding of brain function and dysfunction is severely limited by the lack of technology that will reliably communicate with the cells in the brain for monitoring and intervention. Therefore, one of his main research interests is in the development of multi-functional Neural Prosthesis using MEMS (Micro-Electromechanical Systems) technologies for precise tracking, communication, stimulation and control of neuronal function and dysfunction. Using these novel technologies in models of brain injury, Muthuswamy is interested in understanding the neurochemical and neuroelectrical dynamics that determine neurological outcome and the neuroprotective role of specific genes. There is a great potential for developing exciting new technology for enhancing repair and plasticity mechanisms in the brain after injury that will improve neurological outcomes and greatly enhance quality of lives. Projects are funded by the NIH, the Whitaker foundation, Arizona Biomedical Research foundation and the DARPA.

Expertise

Microelectromechanical systems (MEMS) for Neural communication multi-functional Neural Prosthesis using MEMS (Micro-Electromechanical Systems)

Education

Ph.D., Rensselaer Polytechnic Institute
M.S., Rensselaer Polytechnic Institute
B. Tech., Indian Institute of Technology (India)

Courses

Spring 2014

Courses Taught This Semester
Course Number Course Title
BME 370 Microcomputer Appls in Bioengr
BME 492 Honors Directed Study
BME 493 Honors Thesis
BME 593 Applied Project

Fall 2013

Courses Taught This Semester
Course Number Course Title
ASU 101-BME The ASU Experience
BME 593 Applied Project

Spring 2013

Courses Taught This Semester
Course Number Course Title
BME 351 Circuits for BME
BME 352 Filtering of Signals
BME 593 Applied Project

Spring 2012

Courses Taught This Semester
Course Number Course Title
BME 593 Applied Project
BME 598 Special Topics

Fall 2011

Courses Taught This Semester
Course Number Course Title
ASU 101-BME The ASU Experience
BME 394 Special Topics

Spring 2011

Courses Taught This Semester
Course Number Course Title
BME 370 Microcomputer Appls in Bioengr

Fall 2010

Courses Taught This Semester
Course Number Course Title
BME 598 Special Topics

Spring 2010

Courses Taught This Semester
Course Number Course Title
BME 370 Microcomputer Appls in Bioengr

Fall 2009

Courses Taught This Semester
Course Number Course Title
ASU 101-FSE The ASU Experience
BME 598 Special Topics

Publications and Other Intellectual ContributionsGoogle Scholar

  1. Jitendran Muthuswamy, M Okandan, A Gilletti, M Baker, T Jain. An array of microactuated microelectrodes for monitoring single neuronal activity in rodents. IEEE Trans Biomed Eng (2005).

  2. Jitendran Muthuswamy, M Okandan, N Jackson. Surface Micro-Machined Polysilicon Probes for Neurophysiology. J. Neurosci. Meth (2005).

  3. Jitendran Muthuswamy, M Okandan, T Jain. Electrostatic microactuators for precise positioning of Neural microelectrodes. IEEE Trans Biomed Eng (2005).

  4. M Khraiche, A Zhou, Jitendran Muthuswamy. Acoustic sensor for monitoring adhesion of Neuro-2A cells in real-time. J Neurosci. Meth (2005).

  5. Jain, T, Muthuswamy, Jitendran. Microsystems for spatiotemporal control over delivery of exogeneous molecules to adherent cells (2005).

  6. Muthuswamy, Jitendran, MOkandan, M, Jackson, N. Steerable microelectrodes for neuronal communication (2005).

  7. Muthuswamy, Jitendran, Okandan, M, Gilletti, A, Baker, M, Jackson, N. Movable microprobes for the brain (2005).

  8. Muthuswamy, Jitendran, Okandan, M, Jackson, N. Neural microelectrodes that move (2005).

  9. Saha, R, Gilletti, A, Muthuswamy, Jitendran. Tissue Micromotion Induced Stress Around Brain Implants (2005).

  10. Saha, R, Muthuswamy, Jitendran. Mechanical stress in the brain tissue due to relative micromotion between implants and the brain (2005).

  11. Wang, T, Ehteshami, G, Massia, S, Muthuswamy, Jitendran. GABA immobilized surfaces for assessing biofunctionality of GABA (2005).

  12. Wang, T, Si, J, Muthuswamy, Jitendran. AN ACOUSTIC PLATFORM FOR STUDYING BINDING KINETICS OF NEUROTRANSMITTER -AMINOBUTYRIC ACID (GABA) (2005).

  13. A Zhou, Jitendran Muthuswamy. Acoustic biosensor for monitoring antibody immobilization and neurotransmitter GABA in real-time. Sensors & Actuators B:Chemical (2004).

  14. Book chapter: Muthuswamy, Jitendran. Biomedical Signal processing: An overview. Standard Handbook of Biomedical Engineering and Design. McGraw-Hill Publishers (2003).

  15. Gilletti, A, Jain, T, Muthuswamy, Jitendran. Physiological Micromotion in the Somatosensory Cortex (2003).

  16. Gilletti, A, Jain, T, Okandan, M, Muthuswamy, Jitendran. Overcoming brain micromotion in chronic neural implants (2003).

  17. Khraiche, M, Muthuswamy, Jitendran. Real-time acoustic sensor for Neuronal adhesion (2003).

  18. Khraiche, M, Zhou, A, Muthuswamy, Jitendran. Acoustic Sensors for Monitoring Neuronal Adhesion in Real-Time (2003).

  19. Muthuswamy, Jitendran, Gilletti, A, Jain, T, Okandan, M. Microactuated Neural Probes to Compensate for Brain Micromotion (2003).

  20. Stice, P, Panitch, A, Muthuswamy, Jitendran. Improved Viability of Chronic Neural Implants Using Thin Microelectrodes (2003).

  21. Wang, T, Muthuswamy, Jitendran. Acoustic Immunosensor for Real-time Sensing of Neurotransmitter GABA (2003).

  22. Wang, T, Muthuswamy, Jitendran. Real-time Sensing and Regeneration of GABA Sensor (2003).

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Presentations

  1. Muthuswamy, Jitendran, Castaneda, E, Okandan, M Deep Brain Stimulation Using Microactuated Microprobes. Neural Interfaces Workshop, NINDS, NIH. (Oct 2005).
  2. Muthuswamy, Jitendran, Okandan, M, Gilletti, A, Baker, M, Jackson, N, Jain, T Movable microprobes for the brain. 3rd Annual IEEE EMBS Special Topic Conference on Microtechnologies in Medicine and Biology. (May 2005).
  3. Saha, R, Gilletti, A, Muthuswamy, Jitendran Tissue Micromotion Induced Stress Around Brain Implants. 3rd Annual IEEE EMBS Special Topic Conference on Microtechnologies in Medicine and Biology. (May 2005).
  4. Khraiche, M, Muthuswamy, Jitendran Acoustic Sensors for Monitoring Neuronal Adhesion in Real-Time. Annual meeting of BMES. (Oct 2003).
  5. Wang, T, Muthuswamy, Jitendran Real-time Sensing and Regeneration of GABA Sensor. Annual meeting of BMES. (Oct 2003).

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Research Activity Research Awards

  1. Muthuswamy,Jitendran * . Cyber-Biomedical Systems Curriculum. INTEL CORP (1/1/2014 - 12/31/2014).
  2. Muthuswamy,Jitendran * . Autonomous MEMS probes for intracellular recording. HHS-NIH-NINDS (9/1/2013 - 8/31/2015).
  3. Muthuswamy,Jitendran * . Novel Bioactive Coatings for Chronically Implanted MEMS based Moveable Microelectrodes - PostDoc Arati Sridharan. HHS-NIH-NINDS (4/15/2011 - 4/14/2014).
  4. Muthuswamy,Jitendran * . Targeted RNAi Combinatorial Gene Suppression Using Multimodal Neurochip. AZ ADCC (7/1/2010 - 6/30/2012).
  5. Muthuswamy,Jitendran * . Single neuronal recordings using movable microphobes (See original title below). HHS-NIH-NINDS (9/15/2009 - 8/31/2013).
  6. Muthuswamy,Jitendran * . Single Neuronal Recordings Using Movable Microprobes. HHS-NIH-NINDS (3/1/2007 - 2/28/2013).
  7. Muthuswamy,Jitendran * . Micoractuated Microelectrodes to Assess Cortical Role in Memory Deficits. ABRC (9/1/2005 - 8/31/2008).
  8. Jung,Ranu * , Alexander,Gene Evans , He,Jiping , Helms Tillery,Stephen I , Hu,Jiuxiang , Marzke,Robert F , Massia,Stephen Paul , Matt,Kathleen Sharon , Moore,Michael Charles , Muthuswamy,Jitendran , Myhajlenko,Stefan , Neisewander,Janet Leigh , Nieman,Ronald A , Pauken,Christine Marie , Razdan,Anshuman , Vernon,Brent , . PharmaScan 7016 In-Vivo SpectroscopyImaging System. HHS-NIH-NCRR (6/1/2005 - 5/31/2009).
  9. Muthuswamy,Jitendran * Castaneda,Edward . Deep Brain Stimulation Using Microactuated Microprobes. HHS-NIH-NINDS (4/1/2005 - 3/31/2008).
  10. Muthuswamy,Jitendran * . Microactuated Microelectrode Arrays for Chronic Single Neuronal Monitoring. WHITAKER FDN (11/1/2004 - 10/31/2005).
  11. Muthuswamy,Jitendran * . Antibody Encapsulated Electrochemical Biosensor for GABA. INFRAMAT CORP. (6/1/2003 - 4/26/2004).
  12. Muthuswamy,Jitendran * . MICROFABRICATED ELECTRODE POSITIONERS FOR STUDYING SOMATOSENSORY DEFICITS AFTER GLOBAL ISCHEMIA. WHITAKER FDN (5/1/2001 - 4/30/2004).
  13. Muthuswamy,Jitendran * . STEERABLE MICROFABRICATED MICROELECTRODE DRIVE. HHS-NIH-NINDS (9/21/2000 - 8/31/2004).
  14. He,Jiping * Capco,David George Farin,Gerald E Hoppensteadt,Frank Jassemidis,Leonidas Dimitrios Kim,Bruce Chang-Shik Lai,Ying-Cheng Massia,Stephen Paul Muthuswamy,Jitendran Nielson,Gregory M Panitch,Alyssa Raupp,Gregory Bruce Razdan,Anshuman Si,Jennie . ADVANCED NEURAL IMPLANTS AND CONTROLS. DOD-DARPA (7/13/2000 - 5/31/2004).

* principal investigator

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Service

  1. IEEE Transactions on Neural Systems and Rehabilitation, Associate Editor (2006 - present)
  2. Annual meeting of the Biomedical Engineering Society, Co-chair of session on "Neural signal and information processing, " (2005 - present)
  3. Journal of Neurophysiology, Reviewer (2005 - present)
  4. Friends of International students, Faculty advisor (2004 - present)
  5. Graduate Committee, Member (2004 - present)
  6. Annual meeting of the Biomedical Engineering society, Oct. 1-4, 2003, Co-chair of "Neural recording and stimulation," session (2003 - present)
  7. Annual meeting of the IEEE Engineering in Medicine and Biology Society, Sept. 17-21, 2003, Co-chair of "Nano- and Micro-neurotechnology," session (2003 - present)
  8. Chi Alpha Christian fellowship, Faculty advisor (2003 - present)
  9. Annals of Biomedical Engineering, Reviewer (2000 - present)
  10. Brain Research, Reviewer (2000 - present)
  11. Experimental Brain Research, Reviewer (2000 - present)
  12. IEEE Transactions on Biomedical Engineering, Reviewer (2000 - present)
  13. Journal of Clinical Monitoring, Reviewer (2000 - present)
  14. Faculty search committee (Neural and Tissue engineering), member (2005 - 2006)
  15. National Science Foundation, Member of IGERT pre-proposal review panel (2005)
  16. Faculty search committee (Neural Prosthesis), member (2002 - 2004)

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