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Miles Orchinik

m.orchinik@asu.edu

Assoc Professor
Sols Administration & Faculty
Faculty
Mail Code: 4501

Courses

Spring 2015

Courses Taught This Semester
Course Number Course Title
BIO 282 ConceptualApproachBioMajors II
BIO 492 Honors Directed Study
BIO 493 Honors Thesis

Fall 2014

Courses Taught This Semester
Course Number Course Title
BIO 189 Life Sciences Career Paths
BIO 360 Animal Physiology
BIO 492 Honors Directed Study
BIO 499 Individualized Instruction

Spring 2014

Courses Taught This Semester
Course Number Course Title
BIO 495 Undergraduate Research

Fall 2013

Courses Taught This Semester
Course Number Course Title
BIO 189 Life Sciences Career Paths
BIO 360 Animal Physiology
BIO 495 Undergraduate Research

Spring 2013

Courses Taught This Semester
Course Number Course Title
BIO 394 Special Topics
BIO 493 Honors Thesis
BIO 495 Undergraduate Research

Fall 2012

Courses Taught This Semester
Course Number Course Title
BIO 181 General Biology I
BIO 394 Special Topics
LIA 194 Special Topics

Spring 2012

Courses Taught This Semester
Course Number Course Title
BIO 492 Honors Directed Study
BIO 495 Undergraduate Research
BIO 499 Individualized Instruction
BIO 594 Conference and Workshop

Fall 2011

Courses Taught This Semester
Course Number Course Title
BIO 189 Life Sciences Career Paths
BIO 360 Animal Physiology
BIO 394 Special Topics

Spring 2011

Courses Taught This Semester
Course Number Course Title
BIO 310 Special Problems & Techniques
BIO 492 Honors Directed Study
BIO 493 Honors Thesis
BIO 499 Individualized Instruction
MIC 495 Undergraduate Research

Fall 2010

Courses Taught This Semester
Course Number Course Title
BIO 181 General Biology I
BIO 494 Special Topics
BIO 499 Individualized Instruction

Publications and Other Intellectual ContributionsGoogle Scholar

  1. Breuner, C.W. and Orchinik, M. Pharmacological characterization of intracellular, membrane, and plasma binding sites for corticosterone in house sparrows.. General and Comparative Endocrinology (2009).

  2. Feng, N., Telefont, M., Kelly, K., Orchinik, M., Forster, G.L., Renner, K.L., and Lowry, C.A.. Local perfusion of corticosterone in the rat medial hypothalamus potentiates D-fenfluramine-induced elevations of extracellular 5-HT concentrations: potential role of corticosterone-sensitive organic cation transporter 3 (OCT3).. Hormones and Behavior (2009).

  3. Fokidis, B.K. Orchinik, M., and Deviche, P.. Corticosterone and corticosteroid binding globulin in birds: Relation to urbanization in a desert city.. General and Comparative Endocrinology (2009).

  4. Gasser, P., Orchinik, M., and Lowry, C.A.. Distribution of organic cation transporter 3, a corticosterone-sensitive monoamine transporter, in the rat brain.. Journal of Comparative Neurology 512(4): (2009).

  5. P Gasser, Miles Orchinik. Vasopressin-induced translocation and proteolysis of protein kinase Calpha in an amphibian brain: Modulation by corticosterone. Brain Research (2007).

  6. P Gasser, C Lowry, Miles Orchinik. Corticosterone-sensitive monoamine transport in the rat dorsomedial hypothalamus: potential role for organic cation transporter 3 in stress-induced modulation of monoaminergic neurotransmission. Journal of Neuroscience (2006).

  7. Book chapter: Orchinik, Miles (Author) ,Propper, C R (Author) . Hormone Action on Receptors. Endocrine Disruption: Biological Basis for Health Effects in Wildlife and Humans. Oxford University Press, New York (2006).

  8. N Feng, B Mo, J Johnson, Miles Orchinik, C Lowry, K Renner. Local inhibition of organic cation transporters increases extracellular serotonin in the medial hypothalamus. Brain Research (2005).

  9. A Steiner, L Watkins, A Romanovsky, D Dogan, A Ivanov, S Patel, A Rudaya, D Jennings, Miles Orchinik, T Pace, K O'Connor. A new function of the leptin receptor: mediation of the recovery from lipopolysaccharide hypothermia. FASEB J (2004).

  10. C Breuner, Miles Orchinik, T Hahn, S Meddle, I Moore, N Owen-Ashley, T Sperry, J Wingfield. Differential mechanisms for plasticity of the stress response across latitudinal gradients. American Journal of Physiology: Regulatory, Integrative, and Comparative Physiology (2003).

  11. Miles Orchinik. Special Issue: Stress Hormones and Behavior. Hormones and Behavior (2003).

  12. Edited book: Orchinik, Miles. Stress Hormones and Behavior (2003).

  13. C Breuner, Miles Orchinik. Plasma binding proteins as mediators of corticosteroid action in vertebrates. J. Endocrinol (2002).

  14. Book chapter: Orchinik, Miles,Gasser, P,Breuner, C. Rapid Corticosteroid Actions on Behavior: Cellular Mechanisms and Organismal Consequences. Hormones, Brain and Behavior. Academic Press (2002).

  15. Johnson, P, Gasser, P, Orchinik, Miles, Lightman, S, Lowry, C. Corticosterone induces serotonin accumulation in 3rd ventricular ependyma expressing a novel monoamine transporter (2002).

  16. Martin, R, Orchinik, Miles, Deviche, P, Donaghy-Fonseca, B, Sharp, P. Testosterone treatment of a male songbird inhibits hypothalamo-pituitary gonadotropic activity while inducing gonadal development (2002).

  17. B McEwen, N Weiland, S Carroll, Y Li, Miles Orchinik. Heterogeneity of hippocampal GABAA receptors: regulation by corticosterone. J.Neurosci (2001).

  18. C Breuner, Miles Orchinik. Seasonal regulation of membrane and intracellular corticosteroid receptors in the House Sparrow brain. J.Neuroendocrinol (2001).

  19. C Lowry, K Kedzie, K Renner, F Moore, Miles Orchinik. Rapid changes in monoamine levels following administration of corticotropin-releasing factor or corticosterone are localized in dorsomedial hypothalamus. Horm.Behav (2001).

  20. P Deviche, C Breuner, Miles Orchinik. Testosterone, corticosterone, and photoperiod interact to regulate plasma levels of binding globulin and of free steroid hormone in Dark-eyed Juncos, Junco hyemalis. Gen.Comp.Endocrinol (2001).

  21. Book chapter: Avian Endocrinology. New Delhi and London (2001).

  22. Breuner, C, Orchinik, Miles, Hahn, T, Wingfield, J. Mechanisms of plasticity in the stress response in three subspecies of white-crowned sparrows (2001).

  23. Gasser, P, Orchinik, Miles. Corticosterone modulates proteolysis of Protein Kinase Ca in an amphibian brain: potential mechanism for rapid effects (2001).

  24. C Breuner, D Jennings, M Moore, Miles Orchinik. Pharmacological adrenalectomy with mitotane. Gen.Comp.Endocrinol (2000).

  25. D Jennings, M Moore, R Knapp, L Matthews, Miles Orchinik. Plasma steroid-binding globulin mediation of differences in stress reactivity in alternative male phenotypes in tree lizards, Urosaurus ornatus. Gen.Comp.Endocrinol (2000).

  26. Miles Orchinik, L Matthews, P Gasser. Distinct intracellular, membrane-bound, and plasma binding sites for glucocorticoids in an amphibian. Gen.Comp.Endocrinol (2000).

  27. Cooper, K, Garlick, B, Harrison, J, Orchinik, Miles, Satterlie, R. Human Anatomy and Physiology with Histology Color Atlas. McGraw-Hill (2000).

  28. Book chapter: Gasser, P J,Orchinik, Miles. Membrane receptors for glucocorticoids. Encyclopedia of Stress. Academic Press (2000).

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Presentations

  1. Hassell, J., Collins, V.E., Austin, R.C., Viziteu, C., Lowry, C.A., Orchinik, M. and Renner, K.J. (2012) Intracranial delivery of corticosterone alters extracellular monoamine concentrations in dorsomedial hypothalamus and central nucleus of the amygdala under stress conditions.. Society for Neuroscience Annual Meeting. (Oct 2012).
  2. Hill, K. and Orchinik, M. Identifying shifts in TA’s pedagogical content knowledge (PCK): Outcomes of a "Scientific Teaching" course for biology graduate teaching assistants at a large research university.. National Study of Education in Undergraduate Science: Research Based Undergraduate Science Teaching. (May 2012).
  3. Molinaro, J., Mumaw, L., Barton, S., Renner., K.J., Lowry,C.A., and Orchinik, M. Neuronal and glial localization of corticosterone-sensitive organic cation transporter 3 (OCT3) in hierarchical systems regulating the hypothalamic-pituitary-adrenal (HPA) axis in rats.. Society for Neuroscience Annual Meeting. (Oct 2010).
  4. L. Mumaw, A. Lacagnina, and Orchinik, M. (2009) Seasonal differences in newborn cells in the adult amphibian brain: implications for neuropeptide regulation.. Society for Neuroscience Annual Meeting. (Oct 2009).
  5. Telefont, M., Feng, N., Lowry, C.A., Lukkes, J.L., Orchinik, M., Forster, G.L., Collins,V. and Renner, K.J. The organic cation transporter blocker decynium 22 increases extracellular serotonin concentrations in the rat medial hypothalamus under basal and stress conditions.. Society for Neuroscience Annual Meeting Abstracts. (Oct 2009).
  6. Gasser, P.J., Orchinik, M., Raju, I., and Lowry, C.A. Expression of organic cation transporter 3, a corticosterone-sensitive monoamine transporter, in monoaminergic projection areas in the rat brain: potential role in stress-induced modulation of monoaminergic neurotransmission.. Society for Neuroscience Annual Meeting. (Oct 2008).
  7. Gasser, P.J., Orchinik, M., Raju, I., and Lowry, C.A. Expression of organic cation transporter 3, a corticosterone-sensitive monoamine transporter, in monoaminergic projection areas in the rat brain: potential role in stress-induced modulation of monoaminergic neurotransmission.. Society for Neuroscience Annual Meeting. (Oct 2008).
  8. Orchinik, Miles Corticosteroid-sensitive monoamine transporters in rat brains: implications for 5-HT signaling during stress. ASU / Barrow Neurological Institute Neuroscience Symposium. (Nov 2006).
  9. Gasser, P, Orchinik, Miles, Lowry, C Organic cation transporter 3, a corticosterone-sensitive monoamine transporter, is highly expressed in the medial hypothalamic defensive system. ASU / Barrow Neurological Institute Neuroscience Symposium. (Nov 2006).
  10. Saijo, E, Jennings, D, Orchinik, Miles Region-dependent Pattern of Newborn Cell Proliferation and Survival in an Adult Amphibian Brain. ASU / Barrow Neurological Institute Neuroscience Symposium. (Nov 2006).
  11. Saijo, E, Jennings, D, Orchinik, Miles Region-dependent Pattern of Newborn Cell Proliferation and Survival in an Adult Amphibian Brain. Society for Neuroscience Annual Meeting. (Oct 2006).
  12. Gasser, P, Orchinik, Miles, Lowry, C Organic cation transporter 3, a corticosterone-sensitive monoamine transporter, is highly expressed in the medial hypothalamic defensive system. Society for Neuroscience Annual Meeting. (Oct 2006).
  13. Orchinik, Miles A highly conserved component of the vertebrate response to stressors?. Western Regional Conference on Comparative Endocrinology. (Mar 2006).
  14. Saijo, E, Jennings, D, Orchinik, Miles Distribution and survival of proliferating cells in adult amphibian brains. Western Regional Conference on Comparative Endocrinology. (Mar 2006).
  15. Gasser, P, Lowry, C, Orchinik, Miles Corticosterone-sensitive monoamine transport in the rat dorsomedial hypothalamus: role for organic cation transporter 3 in stress-induced serotonin accumulation. Society for Neuroscience Annual Meeting. (Nov 2005).
  16. Saijo, E, Jennings, D, Orchinik, Miles Widespread distribution of proliferating cells in an adult amphibian brain. Society for Neuroscience Annual Meeting. (Nov 2005).
  17. Feng, N, Johnson, P, Lowry, C, Orchinik, Miles, Renner, K Local inhibition of organic cation transporters increases extracellular serotonin in the dorsomedial hypothalamus. Society for Neuroscience Annual Meeting. (Oct 2004).
  18. Gasser, P, Lowry, C, Renner, K, Orchinik, Miles Expression and function of organic cation transporters in the rat dorsomedial hypothalamus. Society for Neuroscience Annual Meeting. (Oct 2004).
  19. Gasser, P, Lowry, C, Renner, K, Orchinik, Miles Organic cation transporter-mediated uptake of MPP+ in the rat dorsomedial hypothalamus. Society for Neuroscience Annual Meeting.
  20. Orchinik, Miles Brambell seminar series: Mechanism of rapid corticosteroid action in the brain. Henry Wellcome Laboratories in Integrative Neuroscience and Endocrinology, University of Bristol.
  21. Gasser, P, Orchinik, Miles Corticosterone and vasopressin modulate protein kinase C signaling in the amphibian brain. Society for Behavioral Neuroendocrinology Annual Meeting.
  22. Lowry, C, Johnson, P, Gasser, P, Moore, F, Lightman, S, Orchinik, Miles The role of serotonergic systems in emotional behaviour. Winter Meeting of the Association for the Study of Animal Behaviour.
  23. Orchinik, Miles Corticosterone and vasopressin modulate protein kinase C signaling in the amphibian brain. Society for Behavioral Endocrinology Annual Meeting.
  24. Saijo, E, Lowry, C, Orchinik, Miles Characterization of ependymal cells in primary culture from amphibian brain dorsomedial hypothalamus. Society for Neuroscience Annual Meeting.
  25. Orchinik, Miles Mechanism mediating rapid stress hormone action in vertebrate brains. Institute of Neuroscience, University of Newcastle.
  26. Orchinik, Miles Mechanisms of Rapid Stress Hormone Action in Vertebrate Brains. Max Plank Institute for Ornithology.
  27. Fokidis, Haralamobs, Orchinik, Miles, Deviche, Pierre Pharmacological characterization of avian corticosteroid binding globulins (CBG) in desert songbirds: phylogenetic comparisons reveal conserved binding kinematics.. Society for Integrative and Comparative Biology Annual Meeting.
  28. Fokidis, Haralamobs, Orchinik, Miles, Deviche, Pierre Species and life-stage specific variation in avian corticosterone responses associated with urbanization in a desert city.. Society for Integrative and Comparative Biology Annual Meeting.
  29. Saijo, E, Orchinik, Miles Proliferation, differentiation and survival of newborn cells in adult amphibian brains. Society for Integrative and Comparative Biology Annual Meeting.
  30. Breuner, C, Orchinik, Miles Membrane and intracellular glucocorticoid receptors are differentially regulated on a seasonal basis in the avian brain. International Symposium on Avian Endocrinology.
  31. Breuner, C, Orchinik, Miles Membrane and intracellular glucocorticoid receptors are differentially regulated on a seasonal basis in the avian brain. Western and Southwestern Regional Conference Comparative Endocrinology.
  32. Gasser, P, Orchinik, Miles Corticosterone alters arginine vasopressin-induced protein kinase C signaling in an amphibian brain. Western and Southwestern Regional Conference Comparative Endocrinology.
  33. Orchinik, Miles Neurobehavioral actions of corticosteroids during a stress response. Winter Neuropeptides Conference, Biology of the Vertebrate Neuroendocrine Stress System.
  34. Orchinik, Miles Regulation of the HPA Axis: Role of the dorsomedial hypothalamus. National Institutes of Mental Health Research Networks.
  35. Gasser, P, Orchinik, Miles Corticosterone and vasopressin regulate protein kinase C signal transduction in an amphibian brain. Society for Behavioral Neuroendocrinology Annual Meeting.
  36. Orchinik, Miles Multidisciplinary approaches to studying stress and depression. College of Nursing, Arizona State University.
  37. Orchinik, Miles Recent Advances in Corticosterone Receptor Function in the Brain: A Comparative Perspective. Workshop on Steroid Hormones and Brain Function.
  38. Orchinik, Miles Stress - Is it more than a disease? A comparative look at stress and adaptation. Special Symposium, 2001 Meeting of Society for Integrative and Comparative Biology.
  39. Weiss, A, Orchinik, Miles, Matt, K Glucocorticoid receptor levels in the separation stress syndrome of male Siberian dwarf hamsters (Phodopus sungorus). Society for Behavioral Neuroendocrinology Annual Meeting.
  40. Orchinik, Miles Insights into mechanisms of stress using non-traditional model systems. Joint Forum on Research.

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Research Activity Research Awards

  1. Orchinik,Miles * . Collaborative Research: Novel Corticosteroid Actions on Neurotransmitter Function. NSF-BIO (8/1/2009 - 7/31/2014).
  2. Orchinik,Miles * . Neurovisions: Teaching Neuroscience with Neuroimaging Data. Science Approach (2/20/2009 - 12/31/2009).
  3. Orchinik,Miles * . ADULT NEUROGENESIS, REGULATION AND FUNCTION. NSF-BIO (5/1/2004 - 4/30/2008).
  4. Orchinik,Miles * Rawls,Jeffery Alan . CELLULAR MECHANISMS MEDIATING ACUTE STRESS HORMONE ACTION IN BRAIN. NSF-BIO (8/15/2002 - 7/31/2005).
  5. Orchinik,Miles * . HPA REGULATION IN STRESS: THE DORSOMEDIAL HYPOTHALAMUS. INDIANA UNIV-SCH OF MEDICINE (9/30/1999 - 8/31/2002).
  6. Orchinik,Miles * . NEUROENDOCRINE MECHANISMS FOR RESPONDING TO ENVIRONMENTAL STRESS. NSF-BIO (7/1/1998 - 6/30/2000).
  7. Orchinik,Miles * . RAPID SIGNALING PATHWAY FOR CORTICSTEROIDS. NSF-BIO (1/1/1997 - 12/31/2000).

* principal investigator

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Service

  1. Future STEM Sun Devil Family Night at AZ Science Center., Organizer (2012 - present)
  2. Barrett Access and Excellence Committee, Member (2012 - present)
  3. School of Life Sciences / Life Sciences Curriculum Reform Committee, Chair (2010 - present)
  4. State-wide Biology Articulation Task Force, Member (2010 - present)
  5. School of Life Sciences / Undergraduate Programs, Associate Director (2009 - present)
  6. Probationary Review Committee for Graham Boorse, Dept of Integrated Natural Sciences, ASU West, Outside Member (2007 - present)
  7. Graduate Programs Initiatives, Associate Director (2007 - present)
  8. Waggoner Elementary School, Facilitate 1st Annual Science Fair (2007 - present)
  9. Waggoner Elementary School, Guest teacher (2006 - present)
  10. National Science Foundation, Advisory Board, Behavioral Systems Cluster (2006 - present)
  11. Personnel Committee, Member, OISB (2006 - present)
  12. Physiology Curriculum Committee, Chair (2006 - present)
  13. ASU Faculty Development Program, Mentor (2005 - present)
  14. ASU's Faculty Development Program, Mentor (2005 - present)
  15. National Science Foundation, Integrative Biology and Neuroscience, Advisory Board, Neuroendocrinology Panel (2002 - present)
  16. School of Life Sciences / Ask Dr. Biology, Regular contributer (2002 - present)
  17. Barrett Honors Faculty Council, Member (2010 - 2013)
  18. University Animal User’s Committee, Member (2008 - 2013)
  19. SoLS Undergraduate Programs, Associate Director / Associate Dean (2009 - 2012)
  20. SoLS Graduate Programs Committee, Member (2005 - 2010)
  21. Physiology Curriculum Committee, Chair (2006 - 2008)
  22. Graduate Programs Representative for OISB, Member (2005 - 2008)
  23. Graduate Programs Committee, OISB Representative (2005 - 2008)
  24. , Manuscript reviews (ended 2007)
  25. IOS - BEHAVIORAL SYSTEMS CLUSTER, ad hoc reviewer (ended 2007)
  26. Indo-US Science and Technology Forum, ad hoc reviewer (ended 2007)
  27. Netherlands Organisation for Scientific Research, ad hoc reviewer (ended 2007)
  28. SOLS-Learning Resource Center., Brwon Bag presentation, "Applying to Graduate Schools" (ended 2007)
  29. Neuroscience and Behavior PhD Program Working Comittee, Member (2006 - 2007)
  30. Hormones and Behavior, Editorial Board (2001 - 2007)
  31. SoLS Graduate Programs, Interim Associate Director (2006)
  32. Bioimaging / Neuroscience Search Committee, Member (2005 - 2006)
  33. Bioimgaing / Neuroscience Search Committee, Member (2005 - 2006)
  34. Combined Neuroscience Search Committee, Member (2005 - 2006)
  35. Neuroscience Search Committee, Member (2005 - 2006)
  36. University Animal Users Committee AUAC, Member (2005 - 2006)
  37. General and Comparative Endocrinology, Manuscript review (ended 2004)
  38. Animal User’s Committee, Member
  39. Executive Committee, ad hoc member
  40. SoLS, Ask a Biologist Podcast, "Stressed Out"

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