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Randall Nelson

Randal.Nelson@asu.edu

Research Professor
Biodesign MB
Faculty
Mail Code: 6601

BDB 140C (Map)
(480)727-9929

Publications and Other Intellectual ContributionsGoogle Scholar

  1. Borges, C.R; Jarvis, J.; Oran, P.; Nelson, R.W, . Population Studies of Vitamin D Binding Protein Microheterogeneity by Mass Spectrometry Lead to Characterization of its Genotype Dependent O-glycosylation Patterns. J. Proteome Res. (2008).

  2. Niederkofler, E.E., Kiernan, U.A., O’Rear, J., Menon, S., Saghir, S., Protter, A.A., Nelson, R.W., Schellenberger, U.. Detection of Endogenous B-type Natriuretic Peptide at Very Low Concentrations in Patients with Heart Failure. Circulation: Heart Failure (2008).

  3. D Nedelkov, K Tubbs, Randall Nelson. Surface Plasmon Resonance-enabled Mass Spectrometry Arrays. Electrophoresis (2006).

  4. D Nedelkov, Randall Nelson. Surface Plasmon Resonance Mass Spectrometry for Protein Analysis. Methods Mol Biol (2006).

  5. K Tubbs, U Kiernan, E Niederkofler, D Nedelkov, A Bieber, Randall Nelson. Development of Recombinant-based Mass Spectrometric Immunoassay with Application to Resistin Profiling. Anal Chem (2006).

  6. Randall Nelson, U Kiernan, D Nedelkov. The Development of a Multiplex Mass Spectrometric Immunoassay Responsive to Myocardial Infarction. J. Proteome Res (2006).

  7. U Kiernan, D Nedelkov, E Niederkofler, K Tubbs, Randall Nelson. High-throughput Affinity Mass Spectrometry. Methods Mol Biol (2006).

  8. U Kiernan, R Addobbati, D Nedelkov, Randall Nelson. Quantitative Multiplexed C-reactive Protein Mass Spectrometric Immunoassay. J Proteome Res (2006).

  9. D Nedelkov, U Kiernan, E Niederkofler, K Tubbs, Randall Nelson. Investigating Diversity in Human Plasma Proteins. PNAS (2005).

  10. K Tubbs, U Kiernan, E Niederkofler, D Nedelkov, A Bieber, Randall Nelson. High Throughput Mass Spectrometry-Based Protein Phenotyping: Application to Haptoglobin. J. Proteome Res (2005).

  11. A Bieber, K Tubbs, Randall Nelson. Metal ligand affinity pipettes and bioreactive alkaline phosphatase probes: Tools for characterization of phosphorylated proteins and peptides. Mol. Cell. Proteomics (2004).

  12. D Nedelkov, K Tubbs, E Niederkofler, U Kiernan, Randall Nelson. High-throughput comprehensive analysis of human plasma proteins: a step toward population proteomics. Anal. Chem (2004).

  13. Randall Nelson, D Nedelkov, K Tubbs, U Kiernan. Quantitative Mass Spectrometric Immunoassay of Insulin Like Growth Factor 1. J. Proteome Res (2004).

  14. U Kiernan, D Nedelkov, A Tubbs, E Niederkofler, Randall Nelson. Proteomic characterization of novel serum amyloid P component variants from human plasma and urine. Proteomics (2004).

  15. U Kiernan, D Nedelkov, A Tubbs, E Niederkofler, Randall Nelson. Selected expression profiling of full-length proteins and their variants in human plasma. Clin. Proteomics (2004).

  16. C Flynn, C Brophy, P Komalavilas, D Tessier, J Thresher, E Niederkofler, C Dreiza, Randall Nelson, A Panitch, L Joshi. Transduction of biologically active motifs of the small heat shock-related protein HSP20 leads to relaxation of vascular smooth muscle. FASEB J (2003).

  17. D Nedelkov, Randall Nelson. Delineating protein-protein interactions via biomolecular interaction analysis-mass spectrometry. J. Mol. Recogn (2003).

  18. D Nedelkov, Randall Nelson. Design and use of multi-affinity surfaces in biomolecular interaction analysis-mass spectrometry (BIA/MS): a step toward the design of SPR/MS arrays. J. Mol. Recogn (2003).

  19. D Nedelkov, Randall Nelson. Detection of staphylococal enterotoxin B via biomolecular interaction analysis mass spectrometry. Appl. Environ. Microbiol (2003).

  20. D Nedelkov, Randall Nelson. Surface plasmon resonance mass spectrometry: recent progress and outlooks. Trends Biotecnol (2003).

  21. D Nedelkov, Randall Nelson, U Kiernan, E Niederkofler, K Tubbs. Detection of bound and free IGF-1 and IGF-2 in human plasma via biomolecular interaction analysis mass spectrometry. FEBS Lett (2003).

  22. E Niederkofler, K Tubbs, U Kiernan, D Nedelkov, Randall Nelson. Novel mass spectrometric immunoassays for the rapid structural characterization of plasma apolipoproteins. J. Lipid Res (2003).

  23. S Wong, Randall Nelson, U Kiernan, E Sahin, P Jannetto, S Gock, J Jentzen. Toxico-proteomics: MALDI-TOF Mass Spectrometric Immunoassay of Carbohydrate Deficient Transferrin for Assessing Chronic Alcohol Abuse. Therapeutic Drug Monitoring (2003).

  24. U Kiernan, K Tubbs, D Nedelkov, E Niederkofler, E McConnel, Randall Nelson. Comparative urine protein phenotyping using mass spectrometric immunoassay. J. Proteome Res (2003).

  25. U Kiernan, K Tubbs, D Nedelkov, E Niederkofler, Randall Nelson. Detection of novel truncated forms of human serum amyloid A protein in human plasma. FEBS Lett (2003).

  26. D Nedelkov, K Tubbs, Randall Nelson. Design of buffer exchange surfaces and sensor chips for Biosensor Chip Mass Spectrometry. Proteomics (2002).

  27. R Lukas, K Tubbs, A Krivoshein, A Bieber, Randall Nelson. Mass Spectrometry of nicotinic acetylcholine receptors and associated proteins as models for complex transmembrane proteins. Anal. Biochem (2002).

  28. U Kiernan, D Nedelkov, K Tubbs, E Niederkofler, Randall Nelson. High-throughput analysis of human plasma proteins. Am. Biotech. Lab (2002).

  29. U Kiernan, J Black, P Williams, Randall Nelson. High-throughput analysis of hemoglobin from neonates using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Clin. Chem (2002).

  30. U Kiernan, K Tubbs, D Nedelkov, E Niederkofler, Randall Nelson. Comparative phenotypic analyses of human plasma and urinary retinol binding protein using mass spectrometric immunoassay. Biochem. Biophys. Res. Commun (2002).

  31. U Kiernan, K Tubbs, K Gruber, D Nedelkov, E Niederkofler, P Williams, Randall Nelson. High-throughput protein characterization using mass spectrometric immunoassay. Anal. Biochem (2002).

  32. Book chapter: Nedelkov, D (Author) ,Nelson, Randall William (Author) . Biomolecular Interaction Analysis Mass Spectrometry. Mass Spectrometry and hyphenated techniques in neuropeptide research. Wiley (2002).

  33. D Nedelkov, Randall Nelson. Analysis of human protein biomarkers via biomolecular interaction analysis mass spectrometry. Am. J. Kid. Dis (2001).

  34. D Nedelkov, Randall Nelson. Analysis of native proteins from biological fluids by biomolecular interaction analysis mass spectrometry (BIA/MS): exploring the limit of detection, identification of non-specific binding and detection of multi-protein complexes. Biosens. Bioelec (2001).

  35. D Nedelkov, Randall Nelson. Biomolecular Interaction Analysis Mass Spectrometry. Bull. Chem. Technol. Macedonia (2001).

  36. D Nedelkov, Randall Nelson. Biomolecular Interaction Analysis Mass Spectrometry: a comprehensive micro-scale proteomics approach. Amer. Lab (2001).

  37. D Nedelkov, Randall Nelson. Biomolecular Interaction Analysis Mass Spectrometry: a multiplexed proteomics approach. Biopharm (2001).

  38. D Nedelkov, Randall Nelson. Delineation of in-vivo assembled multi-protein complexes via Biomolecular Interaction Analysis Interaction Mass Spectrometry. Proteomics (2001).

  39. E Niederkofler, K Tubbs, K Gruber, D Nedelkov, U Kiernan, P Williams, Randall Nelson. Determination of b-2-microglobulin Levels in Plasma using a High Throughput Mass Spectrometric Immunoassay System. Anal. Chem (2001).

  40. D Nedelkov, A Rasooly, Randall Nelson. Multitoxin biosensor-mass spectrometry analysis: a new approach for rapid, real-time, sensitive analysis of Staphylococcal toxins in food. Int.J. Food Microbiol (2000).

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Presentations

  1. R. Nelson Population Based Proteomics Studies of Type 2 Diabetes. Symposium on Human Variation: A Driver of Personalized Medicine. (Jan 2009).
  2. R. Nelson Mapping Protein Microheterogeneity: Applications in the Development of Biomarkers for Type 2 Diabetes. Mass Spectrometry: Applications in the Clinical Laboratory. (Nov 2008).
  3. R. Nelson Mass Spectrometric Immunoassay in Biomarker Development. 6th CHI Conference on Protein Biomarkers. (Oct 2008).
  4. R. Nelson Arrays in Mass Spectrometry. 35th Federation of Analytical Chemistry and Spectroscopy Societies. (Oct 2008).
  5. R. Nelson Mapping Protein Microheterogeneity: Applications in the Development of Biomarkers for Type 2 Diabetes. Rocky Mountain Conference on Analytical Chemistry. (Jul 2008).
  6. R. Nelson Mapping Human Protein Microheterogeneity: Implications for Clinical Diagnostics. US Human Proteome Organization. (Mar 2008).
  7. R. Nelson The Use of Mass Spectrometric Immunoassay in the Study of Disease. Asilomar Conference on Mass Spectrometry. (Sep 2007).
  8. R. Nelson Addressing Microheterogeneity in Human Plasma Proteomics. G.O.T Summit. (Apr 2007).
  9. R. Nelson Addressing Microheterogeneity in Human Plasma Proteomics. The Mayo Clinic (Rochester). (Apr 2007).
  10. R. W. Nelson High Throughput Mass Spectrometric Immunoassays in Human Plasma Profiling and Targeted Protein Analysis. The Scripps Research Institute. (Feb 2007).
  11. Kiernan, U, Nedelkov, D, Nelson, Randall Biomarker Identification and Validation with Targeted Cardiac Population Proteomics. The 53rd ASMS Conference on Mass Spectrometry and Allied Topics. (Jun 2005).
  12. Nelson, Randall Investigating Diversity in Plasma Proteins. CHI Beyond Genome: The 9th Annual Proteomics Applications in Therapeutic and Diagnostic Developments. (Jun 2005).
  13. Nelson, Randall Population Proteomics: Addressing Diversity in Human Proteins. 2005 AAPS National Biotechnology Conference. (Jun 2005).
  14. Niederkofler, E, Nedelkov, D, Kiernan, U, Tubbs, K, Nelson, Randall Detection of Detrimental Levels of the Biotoxin Staphylococcal Enterotoxin B by Affinity Mass Spectrometry. The 53rd ASMS Conference on Mass Spectrometry and Allied Topics. (Jun 2005).
  15. Nelson, Randall Population Proteomics: Addressing Diversity in Human Proteins. (Apr 2005).
  16. Nelson, Randall, Nedelkov, D, Kiernan, U, Niederkofler, E, Tubbs, K Investigating Protein Diversity in Human Populations. US HUPO-2005. (Mar 2005).
  17. Nelson, Randall Population Proteomics: Addressing Diversity in Human Proteins. The University of Manitoba. (Nov 2004).
  18. Nelson, Randall Protein Chips Linked to Mass Spectrometry. The 29th FEBS Congress. (Jun 2004).
  19. Nelson, Randall, Nedelkov, D, Kiernan, U, Niederkofler, E, Tubbs, K Population Proteomics: Addressing Diversity in Human Proteins. The 52nd ASMS conference on Mass Spectrometry and Allied Topics. (May 2004).
  20. Nelson, Randall Population Proteomics: Addressing Diversity in Human Proteins. Genentech. (May 2004).
  21. Bieber, A, Nelson, Randall, Tubbs, K, Nedelkov, D, Niederkofler, E, Kiernan, U Directed Mass Spectrometry-Based Approaches for Characterization of Protein Phosphorylation. The 52nd ASMS conference on Mass Spectrometry and Allied Topics. (May 2004).
  22. Nelson, Randall Population Proteomics: Addressing Diversity in Human Proteins. Ortho Clinical Diagnostics. (Mar 2004).
  23. Nelson, Randall Population Proteomics: Addressing Diversity in Human Proteins. Amgen. (Jan 2004).
  24. Nelson, Randall Protein Phenotyping using Mass Spectrometric Immunoassay. The 226th National ACS Meeting. (Sep 2003).
  25. Nelson, Randall Adventures in Creating and Arizona Biotech Startup. Arizona Bioindustry Association. (Aug 2003).
  26. Kiernan, U, Nedelkov, D, Tubbs, K, Niederkofler, E, McConnell, E, Nelson, Randall Phenotypic Characterization of Human Urine Proteins Using Mass Spectrometric Immunoassay. The 51st ASMS conference on Mass Spectrometry and Allied Topics. (Jun 2003).
  27. Nedelkov, D, Rasooly, A, Nelson, Randall Mass spectrometry based immunoassays for detection of biological pathogens and warfare agents. The 51st ASMS conference on Mass Spectrometry and Allied Topics. (Jun 2003).
  28. Nelson, Randall Measuring the Chemistry of Life, Discussion Leader, Connecticut College. Gordon Research Conference on Analytical Chemistry. (Jun 2003).
  29. Niederkofler, E, Nedelkov, D, Tubbs, K, Kiernan, U, Nelson, Randall Mass Spectrometry Based Immunoassays for the Detection of Cardiac Biomarkers. The 51st ASMS conference on Mass Spectrometry and Allied Topics. (Jun 2003).
  30. Nelson, Randall High-Throughput Analysis of Human Plasma and Urinary Proteins Using Mass Spectrometric Immunoassay. CHI Molecular Medicine 2003. (Mar 2003).
  31. Nelson, Randall High Throughput Analysis of Human Plasma and Urinary Proteins Using Mass Spectrometric Immunoassay. Labautomation 2003. (Feb 2003).
  32. Nelson, Randall High Throughput Analysis of Human Plasma and Urinary Proteins Using Mass Spectrometric Immunoassay. HPCE2003. (Jan 2003).
  33. Nelson, Randall, Kiernan, U, Niederkofler, E, Tubbs, K, Nedelkov, D High-Throughput Analysis of Human Plasma and Urinary Proteins Using Mass Spectrometric Immunoassay. HPCE 2003, 16th International Symposium on Microscale Separations and Analysis. (Jan 2003).
  34. Nelson, Randall Protein Characterization using Affinity Isolation Mass Spectrometry. Desorption 2002. (Sep 2002).
  35. Nelson, Randall Protein Characterization using Affinity Isolation Mass Spectrometry. IFPAC/BIO 2002. (Apr 2002).
  36. Nelson, Randall Protein Characterization using Affinity Isolation Mass Spectrometry. 222nd National ACS Meeting. (Aug 2001).
  37. Kiernan, U, Tubbs, K, Niederkofler, E, Nedelkov, D, Williams, P, Nelson, Randall High-Throughput Integrated Assay via Combination of Mass Spectrometric Immunoassay, Bioreactive Probes and Parallel Robotic Processing. The 49th ASMS conference on Mass Spectrometry and Allied Topics. (May 2001).
  38. Niederkofler, E, Kiernan, U, Nedelkov, D, Tubbs, K, Gruber, K, Williams, P, Nelson, Randall Quantification of Human Plasma Proteins via Integration of High Throughput Mass Spectrometric Immunoassay System and Functional MALDI targets. The 49th ASMS conference on Mass Spectrometry and Allied Topics. (May 2001).
  39. Nelson, Randall High-Throughput Protein Characterization using Mass Spectrometric Immunoassay (MSIA). 4th IBC Conference on Proteomics. (Mar 2001).
  40. Nelson, Randall, Nedelkov, D Innovations in Proteome Analysis: Biomolecular Interaction Analysis Mass Spectrometry. ABRF 2001. (Feb 2001).

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Research Activity Research Awards

  1. Nelson,Randall William * . Glycemic and non-glycemic determinants of HbA1c and the identification of novel markers of glycemia. NUS (6/1/2013 - 7/31/2015).
  2. Nelson,Randall William * . Next Generation Clinical Mass Spectrometry Platform. VIC Instruments (9/1/2012 - 8/31/2015).
  3. Nelson,Randall William * . Hitachi Collaboration: MSIA of Small Molecules. HITACHI LTD (2/27/2012 - 2/26/2013).
  4. Nelson,Randall William * Borges,Chad Randolph . Team Approach to Translate Novel Biomarkers for Diabetes. HHS-NIH-NIDDK (8/5/2011 - 7/31/2015).
  5. Nelson,Randall William * . Characterizing HDL Heterogeneity in T2DM Patients. NUS (3/15/2011 - 3/31/2014).
  6. Nelson,Randall William * . Mass spectrometric immumoassays for lung cancer. TGen (3/1/2011 - 8/31/2012).
  7. Nelson,Randall William * Borges,Chad Randolph . Novel biomarkers for myocardial infarction based on protein heterogeneity. (3/1/2010 - 12/31/2015).
  8. Nelson,Randall William * Borges,Chad Randolph . Population-Based Proteomic Investigation of Type 2 Diabetes Mellitus. HHS-NIH-NIDDK (3/1/2010 - 2/29/2016).
  9. Nelson,Randall William * Greenes,Robert Kumar,Sudhir Mobley,Michael J Mobley,Michael J . Team Approach to Translate Novel Biomarkers for Diabetes. HHS-NIH-NIDDK (7/1/2009 - 6/30/2011).
  10. Borges,Chad Randolph * Nelson,Randall William Nelson,Randall William . Site-Specific Analysis of Human Cysteine Sulfenic Acid Protein Modifications. HHS-NIH-NCRR (12/1/2007 - 11/30/2010).

* principal investigator

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Service

  1. NIH study section, Cancer Molecular Pathobiology Study Section, REVIEWER (1998 - present)
  2. NIH study section, Center for Scientific Review Special Emphasis Panel, REVIEWER (1998 - present)
  3. NIH study section, National Cancer Institute Special Emphasis Panel, REVIEWER (1998 - present)
  4. NIH study section, National Institute of Allergy and Infectious Diseases Special Emphasis Panel, REVIEWER (1998 - present)
  5. NIH study section, National Institute of Biomedical Imaging and Bioengineering Panel, REVIEWER (1998 - present)
  6. NIH study section, National Institute of Environmental Health Sciences Special Emphasis Panel, REVIEWER (1998 - present)

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